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A Randomized Controlled Trial of Bilateral Movement-based Computer Games Training to Improve Motor Function of Upper Limb and Quality of Life in Sub-acute Stroke Patient

Not Applicable
Completed
Conditions
Stroke
Interventions
Other: Bilateral movement-based computer training
Other: Video-directed conventional training
Registration Number
NCT03618732
Lead Sponsor
Shatin Hospital
Brief Summary

This study aims at investigating whether bilateral movement-based training with computer games could augment motor function of paretic upper limb and improve quality of life in sub-acute stroke patients.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
93
Inclusion Criteria
  • Age between 45-85
  • Diagnosis of ischaemic brain injury or intracerebral hemorrhage by MRI or computed tomography 1 week to 6 months after the onset of current stroke
  • Scoring > 6 of 10 of Abbreviated Mental Test
  • Ability of the paretic hand to hold the game controller (minimal control)
  • Able to give informed consent of the study
  • Can understand instructions given by English or Cantonese
Exclusion Criteria
  • Any additional medical, cardiovascular and orthopaedic condition that would hinder the proper assessment and treatment
  • Having cardiac pacemaker
  • Receptive dysphasia
  • Undergoing drug studies or other clinical trials

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Bilateral movement-based computer trainingBilateral movement-based computer trainingAll subjects underwent 16 sessions of assigned treatment (2 times per week; for 8 weeks; 3 hours standardized rehabilitation program per visit) There was 1.5 hours standardized conventional physiotherapy training a 1.5 hours multi-disciplinary program which consisted of standardized occupational therapy, speech therapy and nursing care. Subjects in Intervention Group will be assigned an additional 30 minutes bilateral movement-based computer games(Able-X) training program of upper limb.
Video-directed conventional trainingVideo-directed conventional trainingAll subjects underwent 16 sessions of assigned treatment (2 times per week; for 8 weeks; 3 hours standardized rehabilitation program per visit) There was 1.5 hours standardized conventional physiotherapy training a 1.5 hours multi-disciplinary program which consisted of standardized occupational therapy, speech therapy and nursing care.
Primary Outcome Measures
NameTimeMethod
Fugl-Meyer Assessment-Upper Extremity Scores (FMA-UE scores) baseline to 4 weeksChange from baseline to 4 weeks

The Fugl-Meyer Assessment (FMA) is a stroke-specific, performance-based impairment index. It is designed to assess motor functioning, balance, sensation and joint functioning in patients with post-stroke hemiplegia. It is applied clinically and in research to determine disease severity, describe motor recovery, and to plan and assess treatment. The FMA-UE scores measure motor impairment of upper extremity. The motor domain includes items assessing movement, coordination, and reflex action of the shoulder, elbow, forearm, wrist and hand.

Fugl-Meyer Assessment-Upper Extremity Scores (FMA-UE scores) baseline to 8 weeksChange from baseline to 8 weeks

The Fugl-Meyer Assessment (FMA) is a stroke-specific, performance-based impairment index. It is designed to assess motor functioning, balance, sensation and joint functioning in patients with post-stroke hemiplegia. It is applied clinically and in research to determine disease severity, describe motor recovery, and to plan and assess treatment. The FMA-UE scores measure motor impairment of upper extremity. The motor domain includes items assessing movement, coordination, and reflex action of the shoulder, elbow, forearm, wrist and hand.

Fugl-Meyer Assessment-Upper Extremity Scores (FMA-UE scores) baseline to followupChange from baseline to 12 weeks (4 weeks after training ended)

The Fugl-Meyer Assessment (FMA) is a stroke-specific, performance-based impairment index. It is designed to assess motor functioning, balance, sensation and joint functioning in patients with post-stroke hemiplegia. It is applied clinically and in research to determine disease severity, describe motor recovery, and to plan and assess treatment. The FMA-UE scores measure motor impairment of upper extremity. The motor domain includes items assessing movement, coordination, and reflex action of the shoulder, elbow, forearm, wrist and hand.

Secondary Outcome Measures
NameTimeMethod
Action Research Arm Test (ARAT) baseline to followupChange from baseline to 12 weeks (4 weeks after training ended)

The Action Research Arm Test (ARAT) is an evaluative measure to assess specific changes in limb function among individuals who sustained cortical damage resulting in hemiplegia. It assesses a client's ability to handle objects differing in size, weight and shape and therefore can be considered to be an arm-specific measure of activity limitation.

Short-Form Health Survey Hong Kong version (HK-SF-36) baseline to 8 weeksChange from baseline to 8 weeks

The Short-Form Health Survey (SF-36) is a widely used, generic, patient-report measure created to assess health-related quality of life (HRQOL) in the general population. SF-36 is the most commonly used generic instrument for measuring quality of life.

Action Research Arm Test (ARAT) baseline to 8 weeksChange from baseline to 8 weeks

The Action Research Arm Test (ARAT) is an evaluative measure to assess specific changes in limb function among individuals who sustained cortical damage resulting in hemiplegia. It assesses a client's ability to handle objects differing in size, weight and shape and therefore can be considered to be an arm-specific measure of activity limitation.

Short-Form Health Survey Hong Kong version (HK-SF-36) baseline to 4 weeksChange from baseline to 4 weeks

The Short-Form Health Survey (SF-36) is a widely used, generic, patient-report measure created to assess health-related quality of life (HRQOL) in the general population. SF-36 is the most commonly used generic instrument for measuring quality of life.

Short-Form Health Survey Hong Kong version (HK-SF-36) baseline to followupChange from baseline to 12 weeks (4 weeks after training ended)

The Short-Form Health Survey (SF-36) is a widely used, generic, patient-report measure created to assess health-related quality of life (HRQOL) in the general population. SF-36 is the most commonly used generic instrument for measuring quality of life.

Action Research Arm Test (ARAT) baseline to 4 weeksChange from baseline to 4 weeks

The Action Research Arm Test (ARAT) is an evaluative measure to assess specific changes in limb function among individuals who sustained cortical damage resulting in hemiplegia. It assesses a client's ability to handle objects differing in size, weight and shape and therefore can be considered to be an arm-specific measure of activity limitation.

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