A Comparative Study on the Effect of Prescribing Dexmedetomidine with Haloperidol in Preventing Delirium
Phase 2
- Conditions
- ?Delirium.Other delirium Delirium of mixed origin Postoperative delirium
- Registration Number
- IRCT20171104037209N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
The entrance criterion included the patients who were candidates for open surgery of coronary arteries and referred to Shahid Chamran Hospital participate in the study
And were free from any psychiatric disease or dementia
He candidates had agreed to participate in the study
Exclusion Criteria
lack of candidate’s assistance
Shortages in data under study
The patient’s death during the surgery or by entrance to ICU
Need to do the surgery again due to bleeding after entrance to ICU
Excessive allergy to haloperidol and phenothiazine
Parkinson (trembling at the time of rest) and weakness in CNS
Glaucoma
Seizure anamnesis
Getting anti-seizure, anti-Parkinson, or lithium drugs
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Delirium? Delirium Exposure? Blood Pressure? During Hospital Occupation? Laboratory variables (sodium and potassium? and variables ABG). Timepoint: Before entering ICU? Before the pump? During the pump? After the pump? The first day of the ICU? The second day of the ICU? Third day of the ICU. Method of measurement: Delirium demonstration by the Richmond Agitation-Sedation Scale Severity of delirium using CAM-ICU Duration of the pump in minutes using the timer The duration of admission to the ICU by day using the count of the days Average arterial blood pressure using a mercury pressure gauge device Receiving haloperidol in the event of delirium with patient file information The amount of pack cell received using patient file information Laboratory variables through blood sampling and determination of laboratory values.
- Secondary Outcome Measures
Name Time Method