Triple-blind clinical trial on the effect of a combination of garlic, silymarin and curcumin in comparison with placebo in the treatment of non-alcoholic fatty liver disease
Phase 2
Recruiting
- Conditions
- fatty liver disease.Fatty (change of) liver, not elsewhere classifiedK76.0
- Registration Number
- IRCT20190602043787N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
increased LFT plus sonographic evidenses of NAFLD
age between 18-70 years
Exclusion Criteria
diabetes mellitus
hypothyioidism
any drug users
sever cardiac disease or sever polmunary disease or past medical history of liver disease,cirrhosis,cancer
pregnancy and lactation
abnormal test include:ANA,HCV Ab,HBC Ab,HBS Ag,Anti TTG IgA,TIBC,Ferritin,SI,ASMA,seroloplasmin
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.decrease in serum level of ALT. Timepoint: at the baseline and 3 months after intervention. Method of measurement: autoanalyzer bt3000.
- Secondary Outcome Measures
Name Time Method Decrease in ultrasonographic grading. Timepoint: at the baseline and 3 months after intervention. Method of measurement: ultrasonography.