Comparison of propofol-based anesthesia and sevoflurane-based anesthesia on postoperative NK-cell activity and receptor expression after hepatectomy
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0006189
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Adults who undergo elective hepatectomy for hepatocellular carcinoma
(older than 18 years old and younger than 76 years old)
-American society of anesthesia (ASA) class I-III
-Patients who have agreed to the trial and signed the subject's consent
- Patients with who have history of side effects from the use of the anesthetic or have contraindication for drugs (a patient suspected of having an allergic reaction to the drug)
- Patients who have liver cancer other than hepatocellular carcinoma (eg Cholangiocarcinoma or metastatic liver tumor)
- Patients who is deemed inappropriate to participate in the clinical trial by the researcher's judgment
- Patients who are allergic to nuts or beans
- Patients who have a history of malignant hyperthermia or risk factors of malignant hyperthermia
- Patients who underwent interventional procedure for HCC
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method K-cell activity and receptor expression
- Secondary Outcome Measures
Name Time Method Proinflammatory cytokines, Oxidative stress marker;Immune cell activation marker;pain stimuli ?? ??;cancer cell activity and angiogenesis related marker