Comparision of two anaesthetic regimens intravenous (propofol-fentanyl) and inhalation (sevoflurane-fentanyl) in intraoperative and postoperative effects in brain tumor surgery
Phase 4
- Conditions
- Health Condition 1: G93- Other disorders of brain
- Registration Number
- CTRI/2019/06/019768
- Lead Sponsor
- Dr Sashmita kumari padhy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
patients undergoing elective neurosurgeries for primary brain tumors of age between 18 to 60 years,of either sex, ASA 1 and 2, GCS 14-15
Exclusion Criteria
patients with cardiac disease,uncontrolled hypertension,uncontrolled dibetic,COPD,hepatic and renal dysfunction,age less than 18 years,more than 60 years,GCS less than 13,ASA 3 and 4,recurrent tumors,patient who had surgery related complication like vascular injury,massive bleeding,injury to vital structre requiring postop ventillatory support,obese patient
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Brain relaxtation ,recovery from anaesthesia like time to eye opening,time to obey commands ,time to extubation after discontinuation of anaesthesia,intraoperative haemodynamics,post extubation haemodynamicsTimepoint: Time taken for eye opening,to obey verbal command ,time for extubation after discontinuation of anaesthesia noted,brain relaxtation assesed by neurosurgeon at time of bone reflection,dural reflection,tumor ressection,dural closure assesesd,haemodynamics preop,preinduction,intubation,pinning,postpinning,skin incision,15 min interval till dural closure,at durl closure,subcutaneous tissue,skin,declamping,preextubation,extubation and immediately after extubation upto 1 hour
- Secondary Outcome Measures
Name Time Method postop side effects pain,PONV,shivering,agitation,convulsion,desaturation.total opoid consumption,total propofol consumption,any bolus dose of propofol and amount,effect site concentration of propofol during induction,intraop period,sevoflurane end tidal concentation and MAC value during intraop periodTimepoint: intraoperative period upto 24 hours after extubation