The effects of NAD+-precursor supplementation on energy metabolism in physically compromised elderly. - NAD Supplementation Study

niversiteit Maastricht0 个研究点目标入组 36 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

暂无简介。

•- Males and females
•- Age * 65 * 80 years;
•- BMI * 20 kg/m2 * 30 kg/m2;
•- Normal physical activity levels: maximum of 1 hour per week engagement in a structured exercise session;
•- 6-minute walking distance of 465 meters or less;
•- Subject should be in sufficient health to participate in the experiments, to be judged by the responsible physician based on the subject's medical history.

•- Not meeting all inclusion criteria;
•- Smoking;
•- Excessive alcohol use and/or drug abuse;
•- Subjects with diabetes mellitus type 2;
•- Significant food allergies or intolerances concerning the study products;
•- Participation in another biomedical study within 1 month before the first study visit, possibly interfering with the study results;
•- Medication use known to hamper subject*s safety during the study procedures;
•- Subjects who use selective serotonin re-uptake inhibitors (SSRI), or selective norepinephrin re-uptake inhibitors (SNRI), or monoamino oxidase inhibitors (MAO-inhibitors), or clomipramine, or St. John*s wort (Hypericum perforatum);
•- Subjects with contra-indications for MRI;
•- Subjects who do not want to be informed about unexpected medical findings;
•- Subjects who do not want that their treating physician to be informed;
•- Co-morbidities to which the intervention or program the may pose as a complicating factor;
•- Inability to participate and/or complete the required measurements.

发起方