An exploratory clinical trial on the effects of nicotinamide mononucleotide (NMN) intake and exercise on skeletal muscle mass and function in older adults.

Not Applicable

• Conditions: Healthy older adults

• Registration Number: JPRN-UMIN000054187
• Lead Sponsor: Tokyo Metropolitan Institute for Geriatrics and Gerontology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-04-19
• Last Update Posted: 2 September 2024
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Not provided

Exclusion Criteria

1).The subjects with a history of heart failure, neurodegenerative disease, or Parkinson's disease. 2).The subjects undergoing treatment for malignancy, atrial fibrillation, arrhythmias, hepatic disorders, renal disorders, cerebrovascular disorders, rheumatism, diabetes mellitus, or other chronic diseases. 3).The subjects undergoing treatment for sleep disorders (insomnia), depression or other psychiatric disorders. 4).The subjects with dementia or an MMSE (Mini-Mental State Examination) score of less than 23 points. 5).The subjects who may develop allergic symptoms to the test food (vitamins), or to any other food or drug. 6).The subjects who habitually consume food supplements or nutritional/energy drinks containing NMN or niacin (vitamin B3, nicotinamide, nicotinic acid amide). 7).The subjects who habitually take medicines, specified health foods, or health foods that may affect aging, such as drugs with antioxidant properties. 8).The subjects who are prohibited from exercising by a physician. 9).Currently, subjects who are participating in another clinical trial, have participated in another clinical trial within the past 3 months, or may participate in another trial during the duration of this trial. 10).The subjects who are known in advance to be unable to attend exercise classes on a regular basis (at least 5 out of 8 times a month). 11).The subjects who are judged to have difficulty communicating in Japanese. 12).The subjects deemed ineligible by the clinical investigator.

Study & Design

• Study Type: Interventional
• Study Design: Not specified