NCT05138302Unknown不适用
A Prospective Multicenter Clinical Study of BRCA and DNA Damage Repair Genes in Blood Samples of Chinese Pancreatic Cancer Patients
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- OS
研究概览
简要总结
This study aims to know the status of BRCA and DDR genes in PDAC patients in China. Peripheral venous blood samples of the patients will be collected for next-generation sequencing of BRCA and DNA damage repair related genes. At the same time, it is necessary to record clinical information such as age, gender, tumor pathological type, tumor stage and grade, whether surgery is performed, the size of postoperative residual lesions, and treatment methods. Prognostic indicators include the association of factors such as PFS, ORR, and DCR are also recorded.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with pancreatic cancer
- •PS score ≤ 2
- •no severe heart, cerebrovascular disease, severe coagulation dysfunction or severe mental disorder
排除标准
- •PS score > 2
- •with severe heart, cerebrovascular disease, severe coagulation dysfunction or severe mental disorder
结局指标
主要结局
OS
时间窗: 2years
Overall survival
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
终止
不适用
China Ovarian Cancer BRCA Testing StudyOvarian CancerNCT03203993AstraZeneca29
招募中
不适用
Asian Multicenter Prospective Study of ctDNA SequencingEndometrial CancerTriple Negative Breast CancerOvarian CancerCervical CancerOvarian Clear Cell CarcinomaNasopharyngeal CarcinomaNCT05099978National Cancer Center, Japan506
已完成
不适用
Prevalence of BRCA in Patients With Ovarian CancerBRCA StatusOvarian CancerNCT02222883AGO Research GmbH530
已完成
不适用
The Study of Molecular Risk Panels (70-gene Assay) in Chinese Breast Cancer PatientsChineseNCT02669745Agendia64
Unknown
不适用
The Registration Program of BRCA1/2 GeneBreast CancerNCT02593435Chinese Anti-Cancer Association8,000
