A Clinical study regarding the changing rate of the bone strength of patients with hormone-sensitive breast cancer under the postoperative endocrine therapy
Not Applicable
- Conditions
- breast cancer
- Registration Number
- JPRN-UMIN000033558
- Lead Sponsor
- Department of Endocrine and Breast Surgery,Kyoto Prefectural Univercity of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Female
- Target Recruitment
- 83
Inclusion Criteria
Not provided
Exclusion Criteria
1)those can not attend University Hospital, Kyoto Prefectural University of Medicine 2)those are considered to be ineligible by the chief investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changing rate for 12 months after starting the postoperative endocrine therapy in following four items derived by an ultrasonic bone measurement system, LD-100 Thickness of distal end of radius Thickness of cortical bone of radius Bone mineral density(BMD) of cancellous bone of radius Elasticity of cancellous bone of radius
- Secondary Outcome Measures
Name Time Method 1) Changing rate in the BMD for the lumbar vertebrae (L1-L4) on DXA 2) Changes in bone metabolism marker and the other date of blood 3) Relation between the bone strength and the activity, BMI and the clinical data 4) Appearance of morbid fracture within the period of this study 5) Efficacy of irisin, plasmalogen and etc as a biomarker and the relation between them and the activity, BMI and the clinical data 6) Stratified analysis of 1)-5)