Evaluation of the combination therapy with L-levothyroxine and L-triiodothyronine in hypothyroid patients

Phase 2

• Conditions: hypothyroidism.; Disorders of thyroid gland; E00, E01,

• Registration Number: IRCT201310204849N4
• Lead Sponsor: Vice chancellor for research, Qazvin University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

New cases of hypothyroidism; Do not consumption of any thyroid hormones in the past three months
Exclusion criteria: Use of any Anti depressant agents; OCP; Anti hyperlipidemic agents; Orliestat; Breast feeding and pregnancy; Opium addiction; Myxedema coma; Use of any drug that interfere with thyroid hormones metabolism; the Patients that registered for other studies in the last month; coronary artery disease

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ipid profile. Timepoint: Before intervention and 12 and 24 weeks after the intervention. Method of measurement: quantitative detective kits in human serum or plasma with photometric method.;Body mass index. Timepoint: Before intervention and 12 and 24 weeks after the intervention. Method of measurement: weight (Kg)/ height(m)2.;Blood pressure. Timepoint: Before intervention and 12 and 24 weeks after the intervention. Method of measurement: Manometer.;Quality of life. Timepoint: Before intervention and 12 and 24 weeks after the intervention. Method of measurement: Questionnaire.;TSH. Timepoint: Before intervention and 12 and 24 weeks after the intervention. Method of measurement: Non competitive immunoradiometric assay (IRMA) for quantitative detection of TSH in human serum or plasma with gamma counter.