Diffusion weighted MRI for evaluation of endometrium and uterine cavity - which phase of the menstrual cycle is optimal for diffusion weighted MR imaging?

• Conditions: infertility; irregular vaginal bleeding; 10038608; 10046828

• Registration Number: NL-OMON32270
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

healthy females with a normal menstrual cycle

Exclusion Criteria

use of oral contraceptives or IUD, caesarean section in history, metal implants

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The DW-MRI images will be scored both for quality and for quantity.<br /><br>Qualitatively, contrast, absence of artefacts, regularity of the image and<br /><br>overall quality will be scored. Quantitatively, the endometrium thickness,<br /><br>signal intensity and ADC of the endometrium versus junctional zone and<br /><br>myometrium will be measured. In addition, the DW-MRI images will be compared to<br /><br>the conventional T2-weighted images.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>