The impact of vitamin D supplementation in chronic heart failure
Not Applicable
Completed
- Conditions
- Chronic heart failureCirculatory SystemOther rheumatic heart diseases
- Registration Number
- ISRCTN17873085
- Lead Sponsor
- niversity of Leeds (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
1. Class II and III heart failure due to left ventricular systolic dysfunction (left ventricular ejection fraction less than or equal to 40%)
2. Stable symptoms for 3 months on maximally tolerated medical therapy with no recent change in medication
3. Able to give informed written consent
4. Aged greater than 18 years, both sexes
Exclusion Criteria
1. Currently taking (or have taken in the previous 3 months) calcium or other vitamin supplements
2. Currently prescribed amlodipine or other calcium channel antagonists (intake of spironolactone will be recorded)
3. CHF due to untreated valvular heart disease
4. History of primary hyperparathyroidism, sarcoidosis, tuberculosis or lymphoma
5. Vitamin D levels greater than 50 nmol/l
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method