Clinical and laboratory Efects of vitamin D supplementation in adolescent with polycystic ovarian syndrome and vitamin D deficiency

Phase 2

Conditions: Adolescent with polycystic ovarian syndrome and vitamin D deficiency.
Polycystic ovarian syndrome
Ovarian dysfunction, unspecified
E28.2
E2

Registration Number: IRCT2016021125732N2

Lead Sponsor: Vice Chancellor for Research, Semnan University of Medical sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 50

Inclusion Criteria

age 14 to 18 years old; people with impaired ovulation or anovulation for oligoovulation (oligo- and / or anovulation); 2 and 3 Hyperandrogenemia clinical hyperandrogenism or There polycystic ovarian morphology on ultrasound and they are deficient in vitamin D, and the study Azargoon et al(1) known as polycystic ovarian syndrome.
Exclusion criteria: people who do not have full consent to participate in this study; Those who did not use vitamin D to regular weekly; Those in the intervention of the symptoms of polycystic ovary syndrome drugs such as birth control pills, metformin, medroxyprogesterone and progesterone intramuscular injection except in the event of amenorrhea has 45 days from the previous cycle dose of 200 mg for the induction periods are used.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Measuring vitamin D. Timepoint: Started. Method of measurement: Laboratory - using the kit for measuring vitamin D, with EUROIMMUN, the UK.

Secondary Outcome Measures

Name	Time	Method
ltrasonography. Timepoint: In 3 to 5 days of menstrual bleeding. Method of measurement: Abdominal Ultrasonography, by one sonographer.;Measuring vitamin D. Timepoint: After the intervention. Method of measurement: Laboratory - using the kit for measuring vitamin D, with EUROIMMUN, the UK.;Blood pressure measurement. Timepoint: After the intervention. Method of measurement: Manometer using a pan with 710 made in Taiwan, the left arm in a sitting position.;Measure weight. Timepoint: After the intervention. Method of measurement: Scales with 100 g.;Measuring stature. Timepoint: After the intervention. Method of measurement: Using tape measure with an accuracy of one centimeter.