Transdermal delivery of fat-soluble vitamins in liposomes: a randomized study

Not Applicable

• Conditions: E84; E56; Cystic fibrosis; Other vitamin deficiencies

• Registration Number: DRKS00016046
• Lead Sponsor: Department of Pediatric Gastroenterology and Metabolic DiseasesPoznan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-12-05
• Study Completion: 2019-01-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

healthy adults

Exclusion Criteria

pregnancy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The mean (or median) change from the baseline in vitamin status in the serum: vitamin A (all-trans-retinol), vitamin D (25-hydroxyvitamin D), vitamin E (alpha-tocopherol), vitamin K (% of uncarboxylated osteocalcin) - after 3 weeks (last 3 days of intervention)

Secondary Outcome Measures

Name	Time	Method
1. Vitamin status in the serum: vitamin A (all-trans-retinol), vitamin D (25-hydroxyvitamin D), vitamin E (alpha-tocopherol), vitamin K (% of uncarboxylated osteocalcin) - after 3 weeks (last 3 days of intervention)<br>2. The mean (or median) change from the baseline in the prevalence of vitamin A, D, E, and K deficiency - after 3 weeks (last 3 days of intervention)<br>3. Planned (depends on feasibility): Concentrations and the mean (or median) change from the baseline of concentrations of vitamin K forms/homologues - after 3 weeks (last 3 days of intervention)