The effect of subzero balanced –modified ultrafiltration technique on chemical and clinical outcomes in cardiopulmonary bypass of pediatrics undergoing cardiac surgery

Not Applicable

• Conditions: Condition 1: Ventricular septal defect. Condition 2: Congenital heart disease. Condition 3: Tetralogy of Fallot.; Ventricular septal defect; Congenital malformation of heart, unspecified; Tetralogy of Fallot; Q21.0; Q24.9; Q21.3

• Registration Number: IRCT20211219053454N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 January 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

weight between 3 to 30 Kg
No renal dysfanction
being born term
normal blood potassium
No transfusions of blood and its products prior to operation
age between 0 to 18

Exclusion Criteria

weight under 3 and above 3 kg
renal dysfunction
being born preterm
abnormal potassium
transfusion of blood and its products
age above 18
administered diuretic prior to operation

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in blood potassium during bypass. Timepoint: Measuring the amount of potassium before the bypass and at half-hour intervals during bypass until its end. Method of measurement: Potassium testing is performed with an ABG measuring device in the cardiac operating room.;Measuring the amount of blood / products after operation. Timepoint: Daily. Method of measurement: Blood and products are in graduated bags that the amount injected is recorded by the ICU nurse.;Measurement of urinary output after surgery. Timepoint: Daily. Method of measurement: Urine is emptied into graduated containers, which are recorded by the ICU nurse on an hourly basis. We calculate the average daily urine output per person.;Evaluation the incidence of cardiac dysrhythmia. Timepoint: Constantly. Method of measurement: By ECG monitoring. In case of occurrence, it will be recorded.

Secondary Outcome Measures

Name	Time	Method
ICU length of stay. Timepoint: Daily. Method of measurement: The patient entering and leaving the ICU is recorded.;Evaluating the GFR during ICU stay. Timepoint: Daily. Method of measurement: GFR determination is calculated by the formula (Schwartz) which has a specific coefficient according to age, height, sex and creatinine.;Measurement of blood transfusion during surgery. Timepoint: Hourly during surgery. Method of measurement: The blood is in graduated bags where the amount transfused is recorded.