NCT03776877Unknown不适用
Evaluation of Clinical and Imaging Criteria, and Plasma Biomarkers of Patients Receiving an Endovascular Treatment for an Acute Ischemic Stroke
适应症
试验速览
- 阶段
- 不适用
- 发起方
- Hopital Foch
- 入组人数
- 4,000
- 试验地点
- 16
- 主要终点
- Clinical outcome
研究概览
简要总结
Study like register with biomarkers samples for patient experiencing acute ischemic stroke, to assess clinical outcomes and different factors that may affect the clinical outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 and older (i.e., candidates must have had their 18th birthday)
- •Neuroimaging demonstrates acute ischemic stroke with large vessel proximal with the use of neuro-thrombectomy devices intended to restore blood flow
- •No upper or lower limits of the neurological severity at baseline (NIHSS).
- •With or without intravenous thrombolysis
- •Oral informed consent (patient and/or trustworthy person)
- •Non-inclusion Criteria:
- •Pregnant or breast-feeding women
- •Patient benefiting from a legal protection
- •Non-membership of a national insurance scheme
排除标准
- 未提供
结局指标
主要结局
Clinical outcome
时间窗: Day 90
modified Rankin score (mRS), score 0 to 6 with 0 = no symptoms and 6 = death.
次要结局
- ASPECT (Alberta Stroke Program Early CT score)(Day O)
- Efficacy on revascularization (>= mTICI 2b)(Day 1)
- Hematoma rate(Day 1)
- Mortality rate(Day 90)
- Parametric imaging(Day 0)
- Imaging data(Day 1)
- Blood sampling for research purpose(Day 0)
- Efficacy on reperfusion (modified Thrombolysis in Cerebral Infarction (mTICI) 2b/3)(Day 1)
- Hemorrhage evaluated by imagery(Day 0)
- Efficacy on clinical outcome (mRS=0-1)(Day 90)
- Complication rate(Day 0)
- Efficacy on functional independence (mRS 0-2)(Day 90)
研究者
研究点 (16)
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