Treatment regimen in Refractory Helicobacter pylori infectio

Phase 4

• Conditions: Patients with refractory Helicobacter pylori infection; Helicobacter pylori; Treatment regimen; Treatment failure

• Registration Number: TCTR20200910007
• Lead Sponsor: Division of gastroenterology, Faculty of Medicine, Siriraj Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-09-10
• Study Completion: 2020-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Age equal to or over 18 years old
2. Refractory Helicobactor pyloridefined by persisitent of infection after 2 or more standard treatment regimens.

Exclusion Criteria

1. Known of allergy to treatment regimen
2. Pregnancy or lactating woman
3. Severe chronic liver or kidnet diseases which affect medication dosages.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Eradication rate At least 4 weeks after treatment completation Negative result of Urea breath test

Secondary Outcome Measures

Name	Time	Method
Risk factors of treatment failure Baseline, during the study is going on and at the end of treatment CYP2C19, drug compliance