Evaluation of Macular Structural and Functional Function Following Extensive Retinal Laser Therapy in Patients With Proliferative Diabetic Retinopathy
- Conditions
- Diabetes Mellitus, Type 2
- Interventions
- Procedure: Panretinal Photocoagulation (PRP)
- Registration Number
- NCT04436900
- Lead Sponsor
- Baqiyatallah Medical Sciences University
- Brief Summary
The present study is a semi-experimental clinical trial that 20 patients (40 eyes) with PDR underwent PRP with ARC with a spot number of 1,200 to 1,500 per eye and spot size 500 micron with a duration of 200 ms. The variables of contrast sensitivity, macula thickness under fovea , BCVA, the width of thyroid under fovea , RNFL thickness in the four areas around the disc, and the quality of life questionnaire of all patients were recorded at the beginning of the study.Retinal and choroid under fovea thickness and RNFL thickness were assessed in four areas, one week and one month after the end of treatment, and all the variables mentioned earlier were evaluated three months after PRP surgery.
This study is single group that the outcomes are compared before and after the intervention
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
- Diabetes Mellitus, Type 2 with PDR
- Having conscious satisfaction
- Patients with a history of other eye diseases
- Patients with a history of previous laser treatment
- Patients with a history of injection of Anti-VGEF
- Patients with Vitreous hemorrhage
- Patients with Macula edema
- Patients with myopia more than -3 diopters or hyperopiamore than +3 diopters
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Intervention group Panretinal Photocoagulation (PRP) 20 patients (40 eyes) with PDR underwent PRP with ARC with a spot number of 1,200 to 1,500 per eye and spot size 500 micron with a duration of 200 ms.
- Primary Outcome Measures
Name Time Method Life Quality up to 3 months A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral, social environment as well as health and disease Which is measured by a quality of life questionnaire
RNFL up to 30 days retinal nerve fiber layer which measured by PP-OCT (optical coherence tomography)
Retinal thickness in the central part of Fovea up to 30 days Measured by SD-OCT
Choroid thickness in the central part of Fovea up to 30 days Measured by EDI-OCT
BCVA up to 3 months best corrected visual acuity which measured by SD-OCT
Contrast sensitivity up to 3 months Contrast sensitivity which measured by Melbourne edge test
Angiography with fluorescein up to 3 months By injecting fluorescein into the vein and then taking an X-ray to diagnose PDR
Physical examination of PDR up to 3 months An eye exam performed by an ophthalmologist will determine if there is retinopathy
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Mohammad Sadegh Bagheri Baghdasht
🇮🇷Tehran, Iran, Islamic Republic of