Food for Thought: Assessing the effect of diet and dietary advice on cognitive function in older people at risk

Not Applicable

Active, not recruiting

Conditions: Cognitive impairment
Neurological - Neurodegenerative diseases

Registration Number: ACTRN12622000065796

Lead Sponsor: niversity of Wollongong

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Active, not recruiting

Sex: All

Target Recruitment: 114

Inclusion Criteria

1) a) Diagnosis of amnestic MCI (single or multidomain) by a geriatrician, neuropsychiatrist or neuropsychologist; b) or be deemed as eligible by achieving a score equivalent to MCI status following completion of the Montreal Cognitive Assessment (T-MoCa) screening test administered via a validated telephone interview tool. A person scoring 13 or less on the Memory Index Score (MIS) within the T-MoCA will be considered to the study.
2) Self-reported subjective memory complaints
3) English-speaking;
4) Aged 60 - 85 y;
5) Able to complete all or all but one of the following basic activities of daily living (unless for physical reason, e.g. arthritis, poor vision): ‘Do you need help to manage everyday activities such as: Personal hygiene?; Dressing?; Taking medication?; Shopping and preparing food?; Transport?; Telephoning?; Finances?; Housekeeping?

Exclusion Criteria

1) Non-English speaking;
2) History of psychiatric (other than mood) disorder in the past 5 y;
3) Underlying additional neurodegenerative condition such as Parkinson’s disease;
4) Other significant neurological history including head injury, epilepsy, or tumour.
5) Taking any of the following medications: donepezil, galantamine, rivastigmine or memantine
6) Scoring 11 or less at the overall T-MoCA or have been diagnosed with Alzheimer’s disease or any other dementia

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Buschke and Grober Free and Cued Selective Reminding Test-Immediate Recall (FCSRT+IR) (auditory anterograde memory functioning). Participants are presented with the same set of 16 pictures, a number of times and after each presentation are asked to recall the items. During each presentation, the items are presented 4 at a time and participants are asked to identify the item that belongs to a category (e.g. animal, item f clothing) so that the category name will act as a cue during retrieval. At recall they are asked to recall the items without any prompting and then with the category as a cue.[ 3 and 6 months after commencement of intervention]

Secondary Outcome Measures