Vitamin c to Improve Tissue healing by Administration of Multiple INtravenous dosages
Recruiting
- Conditions
- wound healing100476351000318410047066
- Registration Number
- NL-OMON41803
- Lead Sponsor
- Meander Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Planned open arterial revascularisation surgery on 1 or 2 legs.;Age >= 18 yrs.;Vascular disease fontaine IIb or higher.
Exclusion Criteria
Age < 18yrs.
Hyperoxaluria.
Patients on dialysis.
Paroxismal nocturnal haemoglobinuria.
G6P deficiency.
Recurrent kidney stones.
Hemochromatosis.
Hemosiderosis.
Usage of deferoxamine (in the past).
Immunological disease.
Pregancy.
Bilateral surgery, other than the revascularisation.
Intolerance for study medication.
Mentally incompetent patients.
Previous participation in this study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Reduction in woundsurface (%) of the surgical wound 30 days after surgery by<br /><br>intravenous suppletion of ascorbic acid in vascular surgery, with correction<br /><br>for the ascorbic acid level.</p><br>
- Secondary Outcome Measures
Name Time Method