THE EFFICACY OF VITAMIN C ORAL SUPPLEMENT ON WOUND HEALING AFTER TOOTH EXTRACTIO
- Conditions
- wound healing of tooth extraction socketVitamin CTooth extractionWound healingAscorbic acid
- Registration Number
- TCTR20180830002
- Lead Sponsor
- Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
1.Patients who have bilaterally symmetrical non-infected premolars needed for extraction, which are usually extracted to make space for orthodontic treatment. Dental caries and retained roots with no periapical lesions or abscess are included.
2.No odontogenic related local or space infection
3.Aged 14-40 years old
4.Absence of uncontrolled medical condition including diabetes mellitus, hematological disorders, immunocompromised or American Society of Anaesthesiologist (ASA) Physical Status I or II
1.Smokers or alcoholics
2.On drug therapy which may interfere with wound healing such as corticosteroids
3.Pregnant or lactating women and taking estrogen-containing contraceptive drugs
4.Psychiatric patients
5.Patients who cannot cooperate with the study and post-operative follow-up
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The healing of the extraction wound Immediately after tooth extraction, on the 7th and 21st day post-extraction The size of the extraction socket measured by using caliper and periodontal probe,The healing of the extraction wound On the 7th and 21st day post-extraction Toluidine blue staining
- Secondary Outcome Measures
Name Time Method Pain The first three days post-extraction VAS
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