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THE EFFICACY OF VITAMIN C ORAL SUPPLEMENT ON WOUND HEALING AFTER TOOTH EXTRACTIO

Phase 4
Recruiting
Conditions
wound healing of tooth extraction socket
Vitamin C
Tooth extraction
Wound healing
Ascorbic acid
Registration Number
TCTR20180830002
Lead Sponsor
Chulalongkorn University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

1.Patients who have bilaterally symmetrical non-infected premolars needed for extraction, which are usually extracted to make space for orthodontic treatment. Dental caries and retained roots with no periapical lesions or abscess are included.
2.No odontogenic related local or space infection
3.Aged 14-40 years old
4.Absence of uncontrolled medical condition including diabetes mellitus, hematological disorders, immunocompromised or American Society of Anaesthesiologist (ASA) Physical Status I or II

Exclusion Criteria

1.Smokers or alcoholics
2.On drug therapy which may interfere with wound healing such as corticosteroids
3.Pregnant or lactating women and taking estrogen-containing contraceptive drugs
4.Psychiatric patients
5.Patients who cannot cooperate with the study and post-operative follow-up

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The healing of the extraction wound Immediately after tooth extraction, on the 7th and 21st day post-extraction The size of the extraction socket measured by using caliper and periodontal probe,The healing of the extraction wound On the 7th and 21st day post-extraction Toluidine blue staining
Secondary Outcome Measures
NameTimeMethod
Pain The first three days post-extraction VAS
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