A comparative study to determine the efficacy between Palonosetron and Aprepitant in the prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy.
Not Applicable
- Conditions
- Health Condition 1: K80- Cholelithiasis
- Registration Number
- CTRI/2022/12/048315
- Lead Sponsor
- Pondicherry Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients belonging to American society of Anesthesiologist physical status 1 and 2.
2.Patients undergoing elective laparoscopic cholecystectomy.
3.Non-Smokers (including smokers who quit smoking for >6 months)
Exclusion Criteria
1.H/o motion sickness
2.Obese patients (BMI > 30 Kg/m2)
3.Patients on oral steroids
4.Pregnant Womens
5.Previous H/o Postoperative nausea and vomiting
6.H/o Arrhythmias on medications.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence of Postoperative nausea and vomiting between intravenous Palonosetron and Oral Aprepitant in patients undergoing laparoscopic cholecystectomy.Timepoint: 24 hrs
- Secondary Outcome Measures
Name Time Method To compare the requirement of rescue antiemetics in between the two groupsTimepoint: 24 hrs