Postoperative new-onset atrial fibrillation in cardiac surgery: An explanatory study of the prophylactic effect of corticosteroids (DECS-PNAF project)

Completed

• Conditions: Atrial fibrillation; cardiac arrhythmias; 10007521; 10007593

• Registration Number: NL-OMON36616
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 180

Inclusion Criteria

Patients who are scheduled to undergo coronary artery bypass grafting, aortic valve surgery, or a combination of both (without concomitant other valve surgery or other additional procedures), who are participating in the DECS trial are eligible for inclusion in the DECS-PNAF project.

Exclusion Criteria

Patients with a history of atrial fibrillation, as well as patients not in sinus rhythm preoperatively, are not eligible for inclusion.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Postoperative new-onset atrial fibrillation</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Mortality<br /><br>Myocardial infarction<br /><br>Myocardial necrosis (cardiac enzymes)<br /><br>Stroke<br /><br>Renal failure<br /><br>Prolonged mechanical ventilation<br /><br>Cardiac arrhythmias other than atrial fibrillation<br /><br>Use of inotropes on the first postoperative day<br /><br>Use of anti-anginal drugs<br /><br>Wound infection<br /><br>Any infection requiring the use of systemic antibiotics<br /><br>Length of stay in the intensive care unit and in the hospital</p><br>