320 Multidetector Computed Tomography Prior to Coronary Artery Bypass Surgery

Withdrawn

• Conditions: Coronary Disease
• Interventions: Radiation: Computed tomography scan

• Registration Number: NCT01169948
• Lead Sponsor: University of Edinburgh

Brief Summary

Recent advances in technology have resulted in the development of scanners that can n image the heart arteries within 10 to 20 minutes but without the need for admission to hospital or insertion of catheters. This means that coronary heart disease may be more readily identified (or ruled out) and allow better diagnosis and treatment of patients with symptoms suggesting coronary heart disease. Here, we propose to assess the latest and most powerful scanners to see if it can accurately diagnose the extent of coronary artery disease and facilitate the planning of heart surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-06
• Study First Submitted: 2010-07-14
• Study First Submitted QC: 2010-07-23
• Study First Posted: 2010-07-26
• Status Verified: 2013-03
• Last Update Submitted: 2013-03-13
• Last Update Posted: 2013-03-14

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• patients who have undergone conventional coronary angiography and have been referred for coronary artery bypass surgery or valve replacement

Exclusion Criteria

• age less than 18
• pregnancy or breast feeding
• inability to undergo computed tomography scanning
• inability to give informed consent
• severe renal failure (serum creatinine >250umol/l or estimated glomerular filtration rate <15ml/min)
• known allergy to iodinated contrast

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients awaiting cardiac surgery	Computed tomography scan	-

Primary Outcome Measures

Name	Time	Method
Coronary artery stenosis defined qualitatively by trained observers and quantitatively by computer software	1 month

Secondary Outcome Measures

Name	Time	Method
Myocardial perfusion defects defined qualitatively by trained observers and quantitatively by computer software	1 month

Trial Locations

Locations (1)

Royal Infirmary of Edinburgh; 🇬🇧 Edinburgh, Scotland, United Kingdom