Symptom QUestionnaire to Ameliorate Symptoms of Hyperemesis (SQUASH) trial

Not Applicable

Completed

• Conditions: Hyperemesis gravidarum; Pregnancy and Childbirth; Excessive vomiting in pregnancy

• Registration Number: ISRCTN01121147
• Lead Sponsor: Central Manchester University Hospitals NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-05-18
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 240

Inclusion Criteria

1. Pregnant women
2. Admitted to participating hospitals with a diagnosis of HG
3. Aged 16 years and above
4. Able to give informed consent
5. HG is defined for this study as excessive vomiting in early pregnancy which results in hospital admission

Exclusion Criteria

1. Onset of first symptoms beyond 14 weeks gestation
2. Previously diagnosed mental health problems
3. Diabetes

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of life at 2 weeks post-discharge as measured by the social functioning scale of the 36-item short form health survey (SF36) questionnaire.

Secondary Outcome Measures

Name	Time	Method
1. Quality of life as measured by the SF36 (total and subscales) at 4 and 6 weeks following discharge<br>2. Nausea and vomiting as measured by the Pregnancy Unique Quantification of Emesis (PUQE) score<br>3. Cost effectiveness of implementing the questionnaire<br>4. Satisfaction with care as measured by the 8-item Client Satisfaction Questionnaire<br>5. Number of days spent in hospital with HG and number of admissions to hospital