Oxygen therapy in severe asthma

Phase 4

Recruiting

• Conditions: Acute asthma; Respiratory - Asthma

• Registration Number: ACTRN12607000131459
• Lead Sponsor: Medical Research Institute of New Zealand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-02-15
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

History of asthma; Presentation to the emergency department with an acute exacerbation of asthma; Forced expiratory volume in 1 second (FEV1) less than or equal to 50% predicted

Exclusion Criteria

Diagnosis of Chronic obstructive pulmonary disease (COPD)/emphysema; Asthma attack requiring mechanical ventilation; Patient unconscious, unable to speak or unable to perform spirometry on arrival; Known or suspected chronic hypercapnic respiratory failure as a result of any of the following disorders - neuromuscular disease, chest wall disease, obesity hypoventilation syndrome.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of patients with an increase in partial pressure of arterial carbon dioxide (PaCO2) greater than or equal to 4mmHg[At 1 hour]