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How Long Must the MRI Follow-up Last to Safely Identify Middle Ear Residual Cholesteatoma

Completed
Conditions
Middle Ear Cholesteatoma
Registration Number
NCT04489550
Lead Sponsor
University Hospital, Montpellier
Brief Summary

Previous studies demonstrated the high diagnostic value of non-echoplanar diffusion weighted magnetic resonance imaging (non-EP DWI) for residual cholesteatoma. However, limited data are available regarding a suitable length of imaging follow-up. The present study aimed to determine the optimal duration of non-EP DWI follow-up for residual cholesteatoma

Detailed Description

A retrospective, monocentric study was performed between 2013 and 2019 and included all patients regularly followed-up after canal wall-up tympanoplasty with at least two non-EP DWI performed on the same 1.5T MRI scanner. MR images were reviewed independently by two radiologists. Sensitivity and specificity values were calculated as a function of time after the surgery. Receiver operating characteristics (ROC) curves were analyzed to determine the optimal follow-up duration.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
17
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
MRI sensitivity and specificity values as a function of the duration of the follow-up1 day

MRI sensitivity and specificity values as a function of the duration of the follow-up. Since no official recommendations are available in the literature, the decision regarding the number of MRIs and the time lapse between any two was left to the discretion of the surgeon

Secondary Outcome Measures
NameTimeMethod
Receiver operating characteristics (ROC) curves1 day

the receiver operating characteristics (ROC) curves

Trial Locations

Locations (1)

Uhmontpellier

🇫🇷

Montpellier, France

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