Prevalence of gastrointestinal disorders in the general population 50 to 75 years in theOmmoord municipality: videocapsule in the Rotterdam study
- Conditions
- Videocapsule endoscopyPrevalenceGastrointestinal disorders
- Registration Number
- NL-OMON26263
- Lead Sponsor
- Erasmus Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 1000
Subject aged 50 untill 74 years old; Participation in the Rotterdam study
Inability or refusal to provide informed consent; Persons with a severe or terminal disease with a life-expectancy of less than 5 years; Dysphagia or other swallowing disorder which makes it impossible to swallow the capsule; Renal failure, eGFR <30 ml/min/1.73m2; Subject has congestive heart failure (NYHA class 3 and 4); Subject has any allergy or other known contraindication to the medications used in the study; High risk of capsule retention: IBD, Personal history of Gastrointestinal surgery other than uncomplicated procedures that would be unlikely to lead to bowel obstruction based on the clinical judgment of the investigator; Cardiac pacemakers or other implanted electro-medical equipment; Subject is expected to undergo MRI examination within14 days after ingestion of the capsule; Presumably or proven congenital long QT syndrome; Participants who use medication that give an extension of the QT- interval; subject has insulin dependent diabetes
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevalence of gastrointestinal disorders, visualized with colon capsule endoscopy
- Secondary Outcome Measures
Name Time Method Participation, prevalence of adverse events; burden of colon capsule endoscopy (CCE); compare results CCE with result endoscopy; referral rate; compare patient characteristics, medication use and demographical aspects between persons with and without found lesions.