Prevalence of gastrointestinal disorders in the general population 50 to 75 years in the Ommoord municipality: videocapsule in the Rotterdam study

Completed

• Conditions: ulcers; 10017943; 10017987; celiac disease; polyps

• Registration Number: NL-OMON44830
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 1000

Inclusion Criteria

- 50-74 years
- participant Rotterdam study

Exclusion Criteria

- Inability or refusal to provide informed consent.
- Persons with a severe or terminal disease with a life-expectancy of less than 5 years.
- An allergy or any other known contraindication to the medication used in this study
- Renal failure, eGFR <30 ml/min/1.73m2
- Congestive heart failure NYHA class III or IV
- Dysphagia or other swallowing disorder which makes it impossible to swallow the capsule.
- High risk of capsule retention: IBD, Personal history of gastrointestinal surgery other than uncomplicated procedures that would be unlikely to lead to bowel obstruction based on the clinical judgment of the investigator.
- Cardiac pacemakers or other implanted electro-medical equipment.
- An MRI scheduled within 14 days after ingestion of the capsule.
- Patients with diagnosed or suspected Congenital Long QT Syndrome
- Patients with concomitant use of drugs that prolong the QT interval

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Prevalence of:<br /><br>- Inflammation, ulcerations and erosions of the gastrointestinal tract,<br /><br>including peptic ulcers<br /><br>- Barrets esophagus<br /><br>- Celiac disease<br /><br>- Gastrointestinal bleeding<br /><br>- Small bowel polyps<br /><br>- Large bowel polyps</p><br>