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Clinical Trials/JPRN-UMIN000006131
JPRN-UMIN000006131
Recruiting
未知

A multicenter, randomized, controlled trial comparing the efficacy of oral fluoroquinolone and aminopenicillin with intravenous Cephalosporin in low-risk pediatric cancer patients with febrile neutropenia. - Oral fluoriquinolones and aminopenicillins versus intravenous Cephalosporin in low-risk pediatric cancer patients with febrile neutropenia.

Tokyo Metropolitan Children's Medical Center0 sites124 target enrollmentAugust 8, 2011

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
Tokyo Metropolitan Children's Medical Center
Enrollment
124
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
August 8, 2011
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Tokyo Metropolitan Children's Medical Center

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • 1\) patients who has a history of stem cell transplantation 2\) acute leukemia or lymphoma patients who are under induction or consolidation chemotherapy 3\) patients with suspected central venous catheter\-related infection 4\) patients with consciousness disturbance (under 15 points of pediatric Glasgow coma scale) 5\) patients with hypotension 6\) patients with hypoxemia (SpO2 less than 95% by pulse oximeter under the room air) 7\) patients with apparent active infection 8\) patients with nausea and vomiting expected difficult to take internal medicine 9\) patients of organ failure (Grade3 or 4 level in NCI CTCAE, such as Hyperbilirubinemia,elevated alanine aminotransferase,elevated aspartate aminotransferase,elevated serum creatinine) 10\) patients administrated other antibiotics (except sulfamethoxazole/trimethoprim as prophylaxis against pneumocystis carinii) 11\) patients with hypersensitivity against Tosufloxacin, Amoxicillin/clavulanate,and cefepime 12\) pregnant patients or those who are suspected pregnancy 13\) patients who are considered inappropriate to join this study by the physicians

Outcomes

Primary Outcomes

Not specified

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