Selenium supplementation in euthyroid patients with thyroid peroxidase antibodies.

Completed

• Registration Number: NL-OMON22027

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

Thyroid peroxidase antibodies >100 kU/l, TSH 0.4-4.0 mE/L, FT4 10-23 pmol/l, T3 1.30-2.70 nmol/L, female sex.

Exclusion Criteria

Use of multivitamin tablets containing selenium in the month preceding inclusion, drug or alcohol abuse, no informed consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change of TPO-antibody concentration, difference in TSH level.

Secondary Outcome Measures

Name	Time	Method
Development of subclinical or overt hypothyroidism and quality of life estimation.