Effect of domperidone and omeprazole in gastro-oesophageal reflux disease in infants between 0 and 2 years.

Completed

• Conditions: GERD (=gastro-esophageal reflux disease); reflux; 10018012

• Registration Number: NL-OMON37309
• Lead Sponsor: Flevoziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 90

Inclusion Criteria

Gastro-oesophageal reflux disease diagnosed by 24-h oesophageal pH monitoring

Exclusion Criteria

1. Gastro-oesophageal reflux disease for which treatment has started. 2. Infants with gastro-oesophageal reflux disease presenting with an apparant life threatening event (ALTE)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Change in reflux time, reflux duration and symptoms before and after treatment<br /><br>as measured by 24-h oesophageal pH monitoring, questionnairies, patient<br /><br>controle</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Physical examination, growth, laboratory results. </p><br>