The efficacy of adjunctive local tranexamic acid for blood salvage in patient undergoing spinal tumor surgery

Not Applicable

• Conditions: Thoracic- Lumbar level Spinal metastasis Thoracic- Lumbar level spinal tumor decompression and instrumentation

• Registration Number: TCTR20190831001
• Lead Sponsor: Department of Orthopedics, Chiangmai University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-31
• Study Completion: 2020-05-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

-Patients undergoing T-L level spinal tumor decompression and instrumentation
-Aged over 18 years

Exclusion Criteria

-Allergic to tranexamic acid
-Coagulopathy or Bleeding tendency
-History of thromboembolic events
-Serum creatinine level > 2 mg/dL
- Pregnancy or breast feeding
- ASA class IV

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative blood loss Since operation finish till postoperative day 3 PBL = Total blood loss (patient's blood volume (PBV) × (Hctpre - Hctpost) / Hctave) - Intraop

Secondary Outcome Measures

Name	Time	Method
Complication 3 days post operative hematoma, infection, wound dehiscence,Deep vein thrombosis, Pulmonary embolism, Myocardial infarctio,Transfusion of blood component within 3 day post-operative 3 days post operative Unit of blood component