Topical Oral Anesthesia Adjuncts in Conventional Intubation: A Randomized Controlled Trial Evaluating the Impact of Topical Oral Anesthesia on First-pass Success Rate
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- First-pass success rate
研究概览
简要总结
This study aims to determine the first-pass success rate in video laryngoscopy and other parameters that topical anesthesia can affect during intubation.
详细描述
In Thailand, conventional intubation or sedation without paralysis is still the most common method of intubation due to the lack of emergency physicians at primary care centers. A pilot study had shown that topical oral anesthesia can improve the first-pass success rate in conventional intubation by direct laryngoscopy. This study aims to determine the first-pass success rate in video laryngoscopy and other parameters that topical anesthesia can affect during intubation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients in emergency department that have indication for conventional intubation
- •Age > 18 yr
排除标准
- •Patient who undergo RSI
- •Patient who falls in cardiac arrest airway algorithm
- •Patient who is currently pregnancy
- •Known allergy to lidocaine
研究组 & 干预措施
Lidocaine spray
Spray lidocaine 10 puffs at oropharynx during preoxygenation if the patient body weight is lower than 60kg, otherwise 15 puffs
干预措施: Lidocaine spray (Drug)
Placebo
Spray normal saline 10 puffs at oropharynx during preoxygenation if the patient body weight is lower than 60kg, otherwise 15 puffs
干预措施: Lidocaine spray (Drug)
结局指标
主要结局
First-pass success rate
时间窗: 1 Year
Comparison of the succession rate of endotracheal tube intubation
次要结局
未报告次要终点