Does the Use of a Videolaryngoscope Modifies Anesthetic Induction ?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Hopital Foch
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Required dose of opioid to counteract nociceptive stimulation
研究概览
简要总结
Videolaryngoscopes become widely used. The aim of this study is to compare anesthetic induction when patients are tracheally intubated using a MacGraph Mac videolaryngoscope or a conventional MacIntosh laryngoscope.
Tracheal intubation induces a nociceptive stimulation. Hypothesis is that the use of a videolaryngoscope induces a less pronounced nociceptive stimulation and, consequently, that it modifies the anesthetic drugs requirement. .
详细描述
All patients will received a standardized anesthetic procedure : combined closed-loop anesthesia system using bispectral index as control variable and two proportional-differential control algorithms, a propofol and a remifentanil target-controlled infusion system. The effectiveness of such a closed-loop anesthesia system has been demonstrated in a prospective, randomized study.
Patients will be randomized in two groups : intubation using a conventional MacIntosh laryngoscope or intubation using a videolaryngoscope.
If our hypothesis is confirmed, the required concentration of remifentanil, an opioid agent, will be reduced in the group using a videolaryngoscope.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient scheduled for a general anesthesia with orotracheal intubation
排除标准
- •predictable risk of difficult mask ventilation or of difficult tracheal intubation
- •necessity of a rapid sequence induction
- •contra-indication to the use of the automated administration of propofol and of remifentanil
- •contra-indication to the use of atracurium
- •Otolaryngology, thoracic surgery, or intracranial surgery
研究组 & 干预措施
Macintosh laryngoscope
Tracheal intubation will be performed using a Macintosh laryngoscope. All patients will received propofol and remifentanil anesthesia.
干预措施: Tracheal intubation (Procedure)
Macintosh laryngoscope
Tracheal intubation will be performed using a Macintosh laryngoscope. All patients will received propofol and remifentanil anesthesia.
干预措施: Propofol and remifentanil anesthesia (Drug)
McGrath Mac videolaryngoscope
Tracheal intubation will be performed using a McGrath Mac videolaryngoscope. All patients will received propofol and remifentanil anesthesia.
干预措施: Tracheal intubation (Procedure)
McGrath Mac videolaryngoscope
Tracheal intubation will be performed using a McGrath Mac videolaryngoscope. All patients will received propofol and remifentanil anesthesia.
干预措施: Propofol and remifentanil anesthesia (Drug)
结局指标
主要结局
Required dose of opioid to counteract nociceptive stimulation
时间窗: 1 hour
Tracheal intubation induces a nociceptive stimulation. Hypothesis is that the use of a videolaryngoscope induces a less pronounced nociceptive stimulation and, consequently, that the required maximal concentration of remifentanil is lower than when a standard laryngoscope is used.
次要结局
- Complications of intubation(one day)
- Characteristics of anesthesia(one hour)
- Characteristics of tracheal intubation(one hour)
- Ergonomic evaluation of the device(one hour)