Dexmedetomidine on propofol requirement during general anaesthesia
Not Applicable
Completed
- Conditions
- Health Condition 1: null- patients posted for spine surgery without any major systemic co morbidities.
- Registration Number
- CTRI/2013/03/003498
- Lead Sponsor
- Institute of Post Graduate Medical Education And Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
Age : 20 â?? 60 yrs
Sex : male and female
ASA-PS status : I or II
Duration of surgery: Within 2 to 3 hrs.
Exclusion Criteria
Patient refusal.
Uncontrolled hypertension, higher degree A-V block.
H/O COPD, obstructive sleep apnea.
Documented hepatic , G-I tract, renal, haematological, psychiatric illness, and seizure disorder.
H/ O allergy.
patient with alcohol abuse.
Pregnancy and breast feeding.
Morbid obesity.
Patients on chronic opioid analgesic , TCA , clonidine, MAO-Inhibitor therapy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To observe the effect of continuous dexmedetomidine infusion on total dose of propofol requirement for maintenance of optimum level anaesthesia in elective spinal surgery.Timepoint: Throughout the duration of the procedure i.e. from the time of induction of anaesthesia till extubation of the patient
- Secondary Outcome Measures
Name Time Method To compare the total requirement of fentanyl during intra operative period between the two groups. <br/ ><br>To compare haemodynamic status between above two groups after induction, during laryngoscopy and intubation, at the time of skin incision, and throughout the intra operative period. <br/ ><br>To compare the recovery profile between two groups as assessed by Ramsay sedation scale. <br/ ><br>to observe any other adverse consequences among the patientsTimepoint: 15 min before starting induction of anaesthesia to 15 min after extubation of the patients