A Retrospective Cohort Study of Patients Who Underwent Curative-intent Esophagectomy for ESCC at a Tertiary Referral Center in South Korea
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 3,131
- 主要终点
- Postoperative complications
研究概览
简要总结
This retrospective cohort study was conducted using the Registry for Thoracic Cancer Surgery at Samsung Medical Center (Seoul, South Korea), which has included all patients who underwent thoracic surgery
详细描述
This retrospective cohort study was conducted using the Registry for Thoracic Cancer Surgery at Samsung Medical Center (Seoul, South Korea), which has included all patients who underwent thoracic surgery
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who underwent curative surgery for esophageal cancer
排除标准
- •cervical esophageal cancer
- •gastroesophageal junction cancer
- •histology other than squamous cell carcinoma
- •patients with Child-Pugh class B or C liver cirrhosis
结局指标
主要结局
Postoperative complications
时间窗: within 90 days after surgery
Complications related to fluid imbalance and portal hypertension, such as ascites, pleural effusion, and chyle leak; complications associated with impaired renal or hematologic function, including acute kidney injury, bleeding, and graft failure; and complications reflecting immune dysfunction and infection susceptibility, including pneumonia and empyema. Complications associated with impaired tissue healing, such as anastomotic leakage, were also analyzed. Liver failure and acute respiratory distress syndrome were considered separately. All complications were defined according to the Esophageal Complications Consensus Group, and their severity was assessed according to the Clavien-Dindo classification.
次要结局
- Overall survival(10 years after surgery)
研究者
Seong Yong Park
Samsung Medical Center
Samsung Medical Center