RETROSPECTIVE ANALYSIS OF PATIENTS WHO HAVE RECEIVED RADICAL CONCURRENT CHEMORADIATION FOR ESOPHAGEAL AND GASTROESOPHAGEAL JUNCTION CANCER
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Primary objective:-
研究概览
简要总结
At TMH, wetreat patients with locally advanced esophageal cancer of the upper thirdesophagus or CA involving the middle or lower third of the esophagus or GEjunction, that is not felt to be amenable to resection in the multidisciplinaryclinic, with definitive radical chemoradiotherapy. Patients with locallyadvanced esophageal or gastroesophageal junction cancer who have undergonesurgical resection, may also be advised adjuvant concurrent chemoradiotherapybased on various features in the histopathology report or based on decisionmade in the joint clinic.5
Since January2011, we have maintained a prospective database of patients treated withradical concurrent chemoradiotherapy. We wish to analyze this dataretrospectively.
We will include all patients who have receivedchemotherapy at Tata Memorial Hospital concurrently with radical radiotherapyfor esophageal and GE junction carcinoma, from January 2011 onwards (to date),whose data has been prospectively entered in a database that has beenmaintained in the medical oncology department at Tata Memorial Hospital.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 95.00 Year(s)（—）
- 性别
- All
入选标准
- •We will include all patients who have received chemotherapy at Tata Memorial Hospital concurrently with radical radiotherapy for esophageal and GE junction carcinoma, from January 2011 onwards (to date), whose data has been prospectively entered in a database that has been maintained in the medical oncology department at Tata Memorial Hospital.
排除标准
- 未提供
结局指标
主要结局
Primary objective:-
时间窗: Acute toxicity weekly while on CTRT | Then at 6 weeks after completion of CTRT | Then every 3 months for first 2 years and | At any point in between as needed.
To assess the toxicity of weekly Carboplatin and Paclitaxel in combination with radical radiotherapy in patients with esophageal and GE junction cancer.
时间窗: Acute toxicity weekly while on CTRT | Then at 6 weeks after completion of CTRT | Then every 3 months for first 2 years and | At any point in between as needed.
次要结局
- Secondary objectives:-(1.Overall survival)