Prospective, Observational,Non-interventional Research of The Correlation of Preoperative Measurement Parameter on the Predicting of Visual Outcomes Among Patients With Idiopathic Macular Holes
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- FAZ area of macular hole at 5 months
研究概览
简要总结
This study retrospectively analyzed the relationship between the preoperative optical coherence tomography(OCT) and optical coherence tomography angiography(OCTA) software related parameters of patients with idiopathic macular hole, the patient's own clinical data and the best corrected visual acuity (BCVA) for at least one month after surgery.
详细描述
After Pars plana vitrectomy combined with removal of the internal limiting membrane (ILM) and air filling, it can not only promote the closure of the macular hole in patients with idiopathic macular hole, but also improve the visual acuity of the affected eye. There are various studies to predict the visual acuity of patients after surgery recovery, but due to many factors that affect the effect of macular hole surgery, the improvement of visual acuity after retinal surgery varies greatly in different eyes. As a new type of ophthalmology device, OCTA plays an important role in measuring the size of the hole and the changes of retinal capillaries. Therefore, this study intends to calculate patient parameters based on OCT and OCTA equipment. Statistical software was used to analyze the relationship between each parameter and the best corrected visual acuity (BCVA) for at least one month after surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •idiopathic MHs, the MH is closed ,and follow-up for at least 1 month after vitrectomy.
排除标准
- •High myopia (≥6 diopters,AL≥26.5mm), increased intraocular pressure (IOP, >21 mm Hg) or glaucoma, severe cataract, severe corneal disease，severe systemic conditions that prevent surgery, and history of ocular trauma, intraocular inflammation, retinal vascular disease, or previous ocular surgery
结局指标
主要结局
FAZ area of macular hole at 5 months
时间窗: at 5 months after surgery
Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography
CRT of macular hole
时间窗: Before surgery
Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography
Macular hole status
时间窗: at 1 month after surgery
macular hole status (open, flat open or closed)
MLD of macular hole
时间窗: Before surgery
Calculation of minimum liner diameter of macular hole with optical coherence tomography angiography
best-corrected visual acuity at 4 months
时间窗: at 4 months after surgery
best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis
CRT of macular hole at 4 months
时间窗: at 4 months after surgery
Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography
Horizontal ellipsoid band missing diameter of macular hole
时间窗: Before surgery
Calculation of Horizontal ellipsoid band missing diameter of macular hole with optical coherence tomography angiography
best-corrected visual acuity at 3 months
时间窗: at 3 months after surgery
best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis
best-corrected visual acuity at 5 months
时间窗: at 5 months after surgery
best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis
FAZ area of macular hole at 4 months
时间窗: at 4 months after surgery
Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography
CRT of macular hole at 5 months
时间窗: at 5 months after surgery
Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography
best-corrected visual acuity at 6 months
时间窗: at 6 months after surgery
best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis
FAZ area of macular hole at 1 month
时间窗: at 1 month after surgery
Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography
FAZ area of macular hole at 6 months
时间窗: at 6 months after surgery
Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography
CRT of macular hole at 1 month
时间窗: at 1 month after surgery
Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography
Choroidal hypertransmission width of macular hole
时间窗: Before surgery
Calculation of Choroidal hypertransmission width of macular hole with optical coherence tomography angiography
Baseline best-corrected visual acuity
时间窗: Before surgery
best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis
best-corrected visual acuity at 1 month
时间窗: at 1 month after surgery
best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis
FAZ area of macular hole
时间窗: Before surgery
Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography
BD of macular hole
时间窗: Before surgery
Calculation of base diameter of macular hole with optical coherence tomography angiography
best-corrected visual acuity at 2 months
时间窗: at 2 months after surgery
best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis
FAZ area of macular hole at 2 months
时间窗: at 2 months after surgery
Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography
FAZ area of macular hole at 3 months
时间窗: at 3 months after surgery
Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography
CRT of macular hole at 2 months
时间窗: at 2 months after surgery
Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography
CRT of macular hole at 3 months
时间窗: at 3 months after surgery
Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography
CRT of macular hole at 6 months
时间窗: at 6 months after surgery
Calculation of central retinal thickness(CRT) of macular hole with optical coherence tomography angiography
次要结局
未报告次要终点