The Role of Anterior Segment Optical Coherence Tomography in Management of Acquired Punctal Stenosis
Overview
- Phase
- Phase 4
- Intervention
- Methylprednisolone eyedrops
- Conditions
- Epiphora Due to Insufficient Drainage
- Sponsor
- Tanta University
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- punctal opening
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
This is a clinical trial study that was conducted on patients with punctal stenosis.We studied the diameter of stenosed puncta before and after treatment with preserved free steroid eye drops using AS-OCT.
Detailed Description
The study was conducted on 40 eyes of 24 patients have acquired inflammatory punctal stenosis and 20 eyes of 10 patients of normal asymptomatic subjects as control group. We studied the external punctal diameter, visibility of the internal punctum and punctal depth before treatment using AS-OCT, and then patients were re-evaluated after one month of treatment with preservative free methylprednisolone 5% eye drops.
Investigators
Amr Mahmoud Awara
assistant professor of ophthalmology
Tanta University
Eligibility Criteria
Inclusion Criteria
- •Patients have acquired inflammatory punctum stenosis complaining of epiphora of different etiologies.
Exclusion Criteria
- •Previous lacrimal surgery.
- •Lid margin malposition such as ectropion, entropion or lid retraction.
- •Medial lid masses obscuring punctum.
- •History of ocular trauma involving lid margin or punctum.
Arms & Interventions
Methylprednisolone eye drops
Preservative free steroids methylprednisolone 5% eye drops (prepared by dilution of methyleprednisolone 500mg in 10 ml distilled water (Solu-Medrol, Pfizer company) was prepared and given for all enrolled cases by the following regimen 5 times/day for 5 days with gradual decrease every third day over the following 2 weeks
Intervention: Methylprednisolone eyedrops
distilled water eyedrops
Distilled water eyedrops instilled 3 times per day for two weeks
Intervention: Methylprednisolone eyedrops
Outcomes
Primary Outcomes
punctal opening
Time Frame: one month
evaluation of punctalopening by OCT