Comparative Evaluation of Chlorhexidine Gel alone and a Combination Gel Chlorhexidine and Metronidazole in treatment of Chronic Periodontitis
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Recording reduction of Relative attachment level using Stent.
研究概览
简要总结
Informed consent is obtained from participating subjects. The subjects are assessed for Gingival Index, Plaque Index, Relative attachment level, Pocket probing depth. Following the recordings of clinical parameters, scaling and root planing will be performed. The selected sites will be randomly allocated into Group I & Group II. The clinical parameters will be recorded at the baseline for both the groups i.e Group I and Group II before the commencement of the treatment. Group I - Scaling and root planing will be done followed by local drug delivery i.e., placement of Chlorhexidine gel. Group II - Scaling and root planing will be done followed by local drug delivery i.e., placement of gel containing combination of Chlorhexidine and Metronidazole. The clinical parameters will be recorded again after 30 days.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of chronic periodontitis having bilateral periodontal pocket of probing depth 4mm-5mm.
- •Both sexes are included.
- •An age group of 20-50 years will be taken.
排除标准
- •Patients who have already received periodontal therapy in past 1 year.
- •Pregnant women & lactating mothers.
- •Women using hormonal contraceptives or on hormonal replacement therapy.
- •Patients having habit of smoking or chewing tobacco.
- •Patients allergic to either Chlorhexidine or Metronidazole.
- •Patients having any known systemic conditions:- Diabetes, Hypertension, Thyroid disorders, or any other condition affecting periodontal status.
结局指标
主要结局
Recording reduction of Relative attachment level using Stent.
时间窗: 0-30 Days
次要结局
- Gingival Index, Plaque Index, Pocket probing depth.(0-30 Days)
研究者
Dr Saheli Paul
Army College of Dental Sciences