A Study to Evaluate the Effects of Anti-HIV Drugs in HIV-Positive Patients Who Also Have Hepatitis C Infection
- Conditions
- HIV InfectionsHepatitis C
- Registration Number
- NCT00001117
- Brief Summary
This study evaluates patients infected with both HIV and Hepatitis C virus (HCV) who are receiving anti-HIV drugs. The purpose of this study is to learn more about HCV infection in patients whose HIV blood level decreases to less than 500 copies/ml.
- Detailed Description
Sixty naive patients with HIV and confirmed hepatitis C who are co-enrolled in another AACTG antiretroviral study that involves the testing of HAART (Highly Active Antiretroviral Therapy) are entered on this prospective study. Patients who are defined as naive have never received specific, active antiretroviral agents that sustain viral suppression below the limit of detection (500 copies/ml) or have received those agents for only a very limited time. HAART is defined as therapy which is likely to result in HIV-1 RNA plasma levels less than 500 copies/ml for at least 16 weeks. Plasma is collected and evaluated during the study for additional quantitative measurements: Hepatitis C virus (HCV) by HCV RNA PCR and HIV-1 RNA levels. All evaluations for HIV-1 RNA are obtained from the co-enrolled study at the following time points: Pre-entry, entry, at least 2 measurements before Week 16, Week 16, and at least 1 measurement after Week 16.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (43)
Harbor UCLA Med Ctr
🇺🇸Torrance, California, United States
Marin County Specialty Clinic
🇺🇸San Rafael, California, United States
Emory Univ
🇺🇸Atlanta, Georgia, United States
Harvard (Massachusetts Gen Hosp)
🇺🇸Boston, Massachusetts, United States
Boston Med Ctr
🇺🇸Boston, Massachusetts, United States
Univ of Cincinnati
🇺🇸Cincinnati, Ohio, United States
Louis A Weiss Memorial Hosp
🇺🇸Chicago, Illinois, United States
Indiana Univ Hosp
🇺🇸Indianapolis, Indiana, United States
Division of Inf Diseases/ Indiana Univ Hosp
🇺🇸Indianapolis, Indiana, United States
Johns Hopkins Hosp
🇺🇸Baltimore, Maryland, United States
Case Western Reserve Univ
🇺🇸Cleveland, Ohio, United States
Ohio State Univ Hosp Clinic
🇺🇸Columbus, Ohio, United States
Univ of Pennsylvania at Philadelphia
🇺🇸Philadelphia, Pennsylvania, United States
Univ of Washington
🇺🇸Seattle, Washington, United States
Willow Clinic
🇺🇸Menlo Park, California, United States
Univ of California / San Diego Treatment Ctr
🇺🇸San Diego, California, United States
San Francisco Gen Hosp
🇺🇸San Francisco, California, United States
Univ of Colorado Health Sciences Ctr
🇺🇸Denver, Colorado, United States
Univ of Southern California / LA County USC Med Ctr
🇺🇸Los Angeles, California, United States
Stanford Univ Med Ctr
🇺🇸Stanford, California, United States
Howard Univ
🇺🇸Washington, District of Columbia, United States
Beth Israel Med Ctr
🇺🇸New York, New York, United States
Northwestern Univ Med School
🇺🇸Chicago, Illinois, United States
Univ of Texas Galveston
🇺🇸Galveston, Texas, United States
Columbia Presbyterian Med Ctr
🇺🇸New York, New York, United States
Chelsea Ctr
🇺🇸New York, New York, United States
Bellevue Hosp / New York Univ Med Ctr
🇺🇸New York, New York, United States
San Mateo AIDS Program / Stanford Univ
🇺🇸Stanford, California, United States
Univ of Hawaii
🇺🇸Honolulu, Hawaii, United States
St Louis Regional Hosp / St Louis Regional Med Ctr
🇺🇸St Louis, Missouri, United States
SUNY / Erie County Med Ctr at Buffalo
🇺🇸Buffalo, New York, United States
Cook County Hosp
🇺🇸Chicago, Illinois, United States
Queens Med Ctr
🇺🇸Honolulu, Hawaii, United States
Charity Hosp / Tulane Univ Med School
🇺🇸New Orleans, Louisiana, United States
Rush Presbyterian - Saint Luke's Med Ctr
🇺🇸Chicago, Illinois, United States
Univ of Minnesota
🇺🇸Minneapolis, Minnesota, United States
Univ of Miami School of Medicine
🇺🇸Miami, Florida, United States
Cornell Univ Med Ctr
🇺🇸New York, New York, United States
Univ of Puerto Rico
🇵🇷San Juan, Puerto Rico
Tulane Univ School of Medicine
🇺🇸New Orleans, Louisiana, United States
Univ of Rochester Medical Center
🇺🇸Rochester, New York, United States
Univ of North Carolina
🇺🇸Chapel Hill, North Carolina, United States
Julio Arroyo
🇺🇸West Columbia, South Carolina, United States