A clinical comparison between 0.5% levobupivacaine and 0.5% levobupivacaine with dexamethasone 8mg combination under USG guided brachial plexus block by supraclavicular approach
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To know the effect of dexamethasone 8mg with 0.5% levobupivacaine on the duration of post-operative analgesia in ultrasound guided supraclavicular brachial plexus block.
研究概览
简要总结
Brachial plexus block is a popular and widely employed regional nerve block technique for anaesthesia and postoperative analgesia for surgeries of the upper extremities. Dexamethasone is a very potent and highly selective glucocorticoid used as anti-inflammatory and immunosuppressant. Steroids have anti-inflammatory as well as analgesic effects. Many studies have successfully proved the usefulness of dexamethasone as an effective analgesic.
This study is designed to know the beneficial effects of addition of dexamethasone to a local anaesthetic in ultra sound guided brachial plexus block by supraclavicular approach.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with ASA class 1 & 2.
排除标准
- •a)Refusal by patients for the block or study.
- •b)Patients with abnormal BT,CT or on anticoagulation therapy, severe anaemia ,hypovolemia ,shock ,septicaemia and h/o seizures.
- •c)Local infection at the site of puncture.
- •d)Allergy to the study drugs.
- •e)History of significant systemic disorders (cardiovascular, respiratory, central nervous system or renal system.
- •f)Patients who are not co-operative and require additional sedatives.
结局指标
主要结局
To know the effect of dexamethasone 8mg with 0.5% levobupivacaine on the duration of post-operative analgesia in ultrasound guided supraclavicular brachial plexus block.
时间窗: Baseline, 0 min( immediately after drug administration), 1min, 3min,5min, 7min, 10min, 15min,20min, 25min, 30min,45min, 60min,90min, 120min,3hr, 4hr,6hr,12hr,24hr
次要结局
- a)the onset of sensory and motor blockade.(b)the duration of sensory and motor blockade.)