The Efficacy of Intravenous Paracetamol Versus Dipyrone for Postoperative Analgesia After Day-case Lower Abdominal Surgery in Children With Spinal Anesthesia: a Prospective Randomized Double-blind Study
Overview
- Phase
- Phase 2
- Intervention
- Paracetamol
- Conditions
- Other Acute Postoperative Pain
- Sponsor
- Baskent University
- Enrollment
- 2
- Primary Endpoint
- Change from pain intensity until postoperative 6 hours
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
We conducted a prospective, randomized double-blind study to compare the effectiveness of intravenous paracetamol and dipyrone for preventing pain during early postoperative period in school-age children undergoing lower abdominal surgery with spinal anesthesia.
Detailed Description
The intensity of postoperative pain was assessed using a visual analog scale (VAS) (0 represented no pain and 10 the worst pain ever experienced) at 15, 30, 60th minutes, and 2nd, 4th, 6th hours postoperatively.
Investigators
Esra Caliskan
Associated Professor
Baskent University
Eligibility Criteria
Inclusion Criteria
- •American Society of Anesthesiologist (ASA) physical status I and II children undergoing elective lower abdominal surgery
Exclusion Criteria
- •increased intracranial pressure hemorrhagic diathesis infection at the puncture site Those with a known history of allergy to the study drugs
Arms & Interventions
Paracetamol
15 mg/kg paracetamol, IV (in the vein)(premixed with 0.9% sodium chloride to a total of 50 ml)single dose
Intervention: Paracetamol
Dipyrone
15 mg/kg IV (in the vein)dipyrone received (premixed with 0.9% sodium chloride to a total of 50 ml), single dose
Intervention: Dipyrone
Outcomes
Primary Outcomes
Change from pain intensity until postoperative 6 hours
Time Frame: Pain intensity recorded until postoperative 6 hours
The intensity of postoperative pain was assessed using a visual analog scale (VAS) (0 represented no pain and 10 the worst pain ever experienced) at 15, 30, 60th minutes, and 2nd, 4th, 6th hours postoperatively.