Brain Imaging in Moderate-late Preterm infants: 'The BIMP study'
Recruiting
- Conditions
- Brain injury, moderate-late preterm neonates
- Registration Number
- NL-OMON24177
- Lead Sponsor
- Isala Women-Children’s Hospital, Zwolle, The Netherlands & Calgary Health Trust, Alberta Children's Hospital Foundation, Canada
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 254
Inclusion Criteria
GA 32-36 weeks;
Exclusion Criteria
1)Congenital malformations of the central nervous system;
2)Chromosomal disorders;
3)Inborn errors of metabolism;
4)Congenital infections;
5)Central nervous system infections;
6)Parents do not speak Dutch or English
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevalence and characteristics of brain injury<br>
- Secondary Outcome Measures
Name Time Method - Relation between perinatal factors and brain injury<br>- Differences in brain volumes between moderate and late preterm infants<br>- Differences in brain measurements between moderate and late preterm infants<br>- Validity of cranial ultrasound for detection of brain injury as compared to MRI (considered the golden standard);<br>- Association brain-imaging findings and neurodevelopmental outcome at 2 years of age