Vitamin E and N-acetylcysteine on prevention of contrast-induced acute kidney injury after coronary catheterization in diabetic patients
Phase 3
- Conditions
- Contrast-induced nephropathy.????????
- Registration Number
- IRCT20200417047114N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Patients with stable coronary disease at risk of acute myocardial infarction, who required coronary artery intervention (angiography)
Patients with acute coronary syndrome, who required coronary artery intervention (angiography)
Diabetic patients
Exclusion Criteria
Patients with hypersensitivity to contrast material
Patients with cardiogenic shock
Patients with pulmonary edema
Patients with acute renal failure
Patients with acute coronary syndrome who underwent angiography or angioplasty for the past 5 days
Patients with recent injection of any contrast material (like radiologic interventions)
Patients with history of dialysis
Pregnant women
Patients with acute myocardial infarction
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 0.5 mg/dl increase in serum creatinine level or 25% compared to baseline was considered as contrast-induced nephropathy. Timepoint: Before and 48 hours after intervention. Method of measurement: Patients' serum test results.
- Secondary Outcome Measures
Name Time Method The frequency of contrast-induced nephropathy. Timepoint: 48 hours after intervention. Method of measurement: Patients' serum test results.