Evaluation the effect of Vitamin E in prevention of cisplatin renal injury

Not Applicable

• Conditions: Cancer.; Malignant neoplasms; C00-C97

• Registration Number: IRCT201701011497N5
• Lead Sponsor: Vice Chancellor for Research,Isfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Inclusion criteria were age = 18 years old and having glomerular filtration rate (GFR) > 80 ml/min.
Exclusion criteria were comorbidity that affected renal function (such as diabetes mellitus, hypertension, and past history of renal dysfunction); previous chemotherapy and treatment with other supplementation.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in serum creatinine and the glomerular filtration rate. Timepoint: From cycle 1 to 4. Method of measurement: laboratory.

Secondary Outcome Measures

Name	Time	Method
Changes in neutrophil gelatinase-associated lipocalin (NGAL) levels. Timepoint: From cycle 1 to 4. Method of measurement: Elisa kit.