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临床试验/NCT00718302
NCT00718302
已完成
不适用

Ankle Fracture Plating: A Multicenter Randomized Trial Comparing Lateral and Antiglide Plating in Displaced Lateral Malleolus Fractures

Boston Medical Center10 个研究点 分布在 2 个国家目标入组 249 人2008年6月

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Ankle Injuries
发起方
Boston Medical Center
入组人数
249
试验地点
10
主要终点
Percentage of Nonpalpable Hardware
状态
已完成
最后更新
9年前

概览

简要总结

The role of operative fixation of unstable, displaced lateral malleolus fractures is well-established (Mayer, Mak, and Yablon). However, the optimal type of fixation remains the subject of debate. Lag screw fixation alone is only appropriate for long oblique fractures in younger patients (Tornetta). For all other patients, the choices for fibular stabilization most commonly involve the use of plates and screws which can be placed on either the lateral or posterior side of the bone, with or without lag screws. Lateral plating remains the most popular option, but since the description of posterior plating in 1982 (Brunner), reports in the literature have demonstrated some advantages of posterior over lateral plating (Ostrum, Treadwell, Winkler, and Wissing) . These advantages include less dissection, less palpable hardware, and decreased likelihood of intra-articular screw placement. However, there is only a single retrospective study in the published literature directly comparing these two methods (Lamontagne).

详细描述

Since it was first described in 1982, posterior antiglide plating has been presented as an attractive alternative to lateral plating of distal fibula fractures. Biomechanical studies have shown it to be a stronger construct than lateral plating, and other purported advantages include less dissection, decreased potential for intra-articular screw placement, and less palpable hardware decreasing the need for hardware removal.However, although posterior plating has become an accepted technique for operative management of these injuries, there is little clinical information in the literature regarding this treatment, and only one published retrospective study directly comparing posterior to lateral plating. In 1996, Ostrum published a prospective study evaluating posterior plating in 32 patients, but only compared his results to a cohort of patients treated with lateral plating that was not part of his actual study group.Patel et al. recently presented a retrospective comparison of both techniques, but their study only included 29 patients in the lateral plating group and 23 in the posterior group.In both these studies, posterior plating was felt to be superior to lateral plating based on both the decrease in complications/re-operations related to symptomatic hardware, and improved function and pain scores. However, in a much larger study, Lamontagneet al. showed no differences in operative time, complications or hardware removal rates in 193 patients reviewed retrospectively, and concluded that they could not recommend one treatment method over the other. They even elected not to proceed with a planned prospective study based on their results.A recent retrospective analysis of 70 patients showed a 43% incidence of need for hardware removal due to pain, with 30% of these patients having peroneal tendon lesions identified intra-operatively.

注册库
clinicaltrials.gov
开始日期
2008年6月
结束日期
2012年12月
最后更新
9年前
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

责任方
Principal Investigator
主要研究者

Paul Tornetta, III, M.D.

Principal Investigator

Boston Medical Center

入排标准

入选标准

  • Patients aged 18 - 85
  • Closed Unstable Supination Eversion type Weber B fibula fracture
  • Soft tissue amenable to operative treatment
  • Opt for surgical treatment of their fracture
  • Willing to follow up for 1 year
  • Consent to be randomized

排除标准

  • Aged \< 18 or over 85
  • Open fracture
  • Prisoners
  • Unlikely to followup
  • Non english speaking
  • Pre-existing arthrosis of the ankle
  • Limitation in lower extremity function that would affect outcome scoring
  • Significant anterior comminution precluding antiglide fixation
  • Bilateral Fracture

结局指标

主要结局

Percentage of Nonpalpable Hardware

时间窗: 3 months, 6 months, 12 months

Percentage of Participants with Nonpalpable Hardware

次要结局

  • SMFA - Bother Index(3 months, 6 months, 12 months)
  • Percentage Normal Peroneal Tendons(3 months, 6 months, 12 months)
  • The Short Musculoskeletal Functional Assessment (SMFA) Score(3 months, 6 months, 9 months)
  • American Orthopedic Foot and Ankle Society Score (AOFAS) Scores(3 months, 6 months, 12 months)

研究点 (10)

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