Effect of tranexamic acid on blood loss after coronary artery bypass grafting in patients treated with clopidogrel
Phase 2
- Conditions
- Bleeding after CABG.Haemorrhage and haematoma complicating a procedure, not elsewhere classified
- Registration Number
- IRCT201309125381N8
- Lead Sponsor
- Vice-chancellor of Research Babol University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
patients undergoing on-pump CABG who received clopidogrel with their last ingestion less than5 days preoperatively.
Exclusion criteria: previous cardiac surgery; hematocrit less than 33%; platelet count less than 100,000/mL; or allergy to tranexamic acid; renal failure(cr>2), hepatic failure; history of bleeding diasthesis; abnormal coagulation test; previous cardiac surgerry.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bleeding after CABG. Timepoint: 24 houres. Method of measurement: Measuring mediastinal drainage into the chest bottle.
- Secondary Outcome Measures
Name Time Method Blood and blood products transfusion after CABG. Timepoint: 24 hours. Method of measurement: Measuring units of blood and blood products tranfused during and after CABG.