Blood Loss Reduction: Effect of Tranexamic Acid Routes in Different Knee Prosthesis: A Randomized Controlled Trial.
Phase 3
Completed
- Conditions
- Patients with primary osteoarthritis knee scheduled for unilateral primary total knee arthroplasty (TKA)Primary TKA,open-box knee prosthesis,closed-Tranexamic acid
- Registration Number
- TCTR20170618001
- Lead Sponsor
- aresuan university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 228
Inclusion Criteria
All patients with the diagnosis of primary osteoarthritis knee scheduled for unilateral primary total knee arthroplasty (TKA) in Naresuan university hospital were enrolled.
Exclusion Criteria
Patients with preop hemoglobin level less than 10g/dL, previous history of thromboembolic event, renal insufficiency, cardiovascular disease or cerebrovascular accident were excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood loss 6,12,24,48,72,96 hr postop Perioperative blood loss, drainage blood loss, postop hemoglobin level
- Secondary Outcome Measures
Name Time Method pain score 6,12,24,48,72,96 hr postop visual analogue scale,knee flexion, Straight leg raising, extension lag 6,12,24,48,72,96 hr postop goniometer